GO:1990726 cellular_component Lsm1-7-Pat1 complex
| PAG Title | GO:1990726 cellular_component Lsm1-7-Pat1 complex |
| PAG ID | TAX034331 |
| Type | A |
| Source Link |  GOA |
| Publication Reference | NA |
| PAG Description | A conserved, heteroheptameric, cytoplasmic protein complex composed of Lsm1, Lsm2, Lsm3, Lsm4, Lsm5, Lsm6, Lsm7, and Pat1, or orthologs thereof, that shows a strong binding preference for oligoadenylated RNAs over polyadenylated RNAs. May bind further associated proteins. Facilitates the deadenylation-dependent decapping of mRNA in the P-body thereby regulating mRNA decay and subsequent degradation by the 5' to 3' pathway. |
| Species | Homo sapiens |
| nCoCo Score | 1,217 |
| Base PAG ID | TAX034331 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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